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Human Longevity
South San Francisco, California

Senior Physician - South San Francisco

Internal MedicineFull-Time

Compensation

Pay not listed

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Job Description

Join Human Longevity and be a part of revolutionizing the future of medicine!

Healthcare, reimagined. Proactive. Precise. Personalized.

About Human Longevity

At Human Longevity, our mission is to revolutionize medicine by bridging the gap between health span and life span, where our members continue to enjoy optimal health and functionality well into 100+.

We provide preventative, predictive and personalized longevity precision medicine that enhances performance and functionality. Our goal is to help our clients enjoy every facet of life by empowering them with technology input and actionable health plans.

At Human Longevity, we believe in the science behind longevity medicine, not sensationalism.

Our AI-data driven longevity platform blends data and cutting-edge science to create personalized goals for our members, delivering exceptional care all in a relaxing luxurious environment.

What Is the Opportunity?

The Physician will report to Medical Director of clinic location, with oversight by leadership of Nucleus Medical Group (medical group partnered with Human Longevity).

They will assume responsibility for a wide scope of care, including ordering and evaluating tests as well as performing treatments as clinically indicated. They will be responsible for delivering the longevity precision medicine to our members as set forth by the leadership team.

This role requires a focus on optimal proactive preventive care, longevity medicine guidance, optimization of client retention, and passion in growing our AI technology as well as furthering longevity science.

Join our team of highly trained, passionate clinicians!

What’s in It for You?

You will be working with world renowned specialists and longevity trailblazers.

From our Buck Institute partnership along with our internal team of medical leaders, Human Longevity is a place where clinicians not only save lives daily, but can also thrive in knowledge-based growth, connections to community thought leaders, and scientific advancements.

As our team members are essential to the lives of our members and also to our company, you will receive the full membership advantages of Human Longevity for your own personal health as well. Our passion is in extending not just the lives of our members, but also of our team members.

What Will You Do?

The Physician will provide advanced clinical medical care in the examination, assessment, and provision of comprehensive care for our members. Our clinicians maintain a clean work environment as well as positivity towards staff and assist in tech as well as clinical developments of our company.

Clinicians also are responsible in directing and coordinating the activities of medical assistants they work with, while consulting with and taking direction from medical director. A harmonious work environment is crucial to our company. We encourage mutual learning from all of our clinicians.

Tasks and Responsibilities

Provide precision medicine-based concierge longevity care to roughly 200 clients

As the client’s private longevity precision medicine physician, he/she is responsible for providing client’s medical and health management services

Participate in the Nucleus Medical Group, focusing on day-to-day clinical operations and development, as well as personalized, prevention focused medical care and targeted health promotion services

Provide regular clinical support within the practice and also via telemedicine modalities (e. g. phone, email, video chat)

Provide direct clinical oversight to a group of pre-assigned clients; assure high client satisfaction and high client retention rate

Coordinate with HLI’s Care Delivery System daily to deliver medical care and to support client’s consultation services with medical specialist

Supervise a team of nurses, technologists, and clinicians in a client-centered model, help clients set health goals, and support daily clinical work

Help contribute to consolidated report development for quality control purposes

Regularly review and deliver consolidated reports to clients and develop health goals

Provide clinical management for clients in collaboration with multidisciplinary internal and external clinician partners

Assist in training and development of internal and external longevity precision care and specialist physicians committed to delivery of genomics-based, technology-driven medicine

Minimum Qualifications (Must have)

At least ten years of experience working as a primary care-oriented physician with background in internal medicine or family practice

Have the passion and skills to delight clients with service-oriented approach and empathetic client interaction.

Board Certified or pending Board certification in Internal Medicine or Family Medicine. Other certifications considered on a case-by-case basis.

  • Must have or be willing (and qualified) to obtain an unrestricted medical license for California
  • Commitment to practice of science-based medicine
  • Demonstrate ability to manage, motivate, and empower diverse clinical teams
  • Interest in or relevant experience in implementation of innovative medical care models

Excellent Communication Skills

Strong leadership and team-oriented with excellent interpersonal skills.

Preferred Qualifications

  • Functional and/or Integrative Medicine training
  • Experience working in direct pay or concierge medical settings
  • Able to thrive in an often ambiguous, challenging, and fast-paced environment
  • Experience in working with early stage medical or biotech companies
  • Health coaching and behavioral change training
  • Knowledge of clinical genetics

Compensation Package

  • Competitive compensation and benefits
  • Plus Stock Options

What Do You Need to Succeed?

To ensure success, the Physician will be detail-oriented with the ability to deliver care in a compassionate manner; personalizing care that ensures optimal health and comfort. Collaboration amongst departments of services and care are crucial in our clinician’s success as well as the success of our company. We also encourage our physicians to engage in technological and medical advancements and developments.

Human Longevity, Inc. is an equal opportunity employer

Key Responsibilities

The physician will provide advanced, personalized longevity precision medicine to clients while overseeing clinical operations and coordinating with a multidisciplinary team. They are responsible for managing client health goals, performing clinical assessments, and supervising medical staff to ensure high-quality care and retention.

Requirements

Candidates must have at least ten years of experience in primary care, internal medicine, or family practice, and hold or be eligible for a California medical license. Board certification in Internal Medicine or Family Medicine is required, along with strong leadership skills and a passion for science-based longevity medicine.

Qualifications

Education
Professional certificate or licensure
Experience
10+ years of experience

Key Skills

Clinical LeadershipConcierge MedicineFunctional MedicineTeam ManagementPatient CareData-driven Medicine

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Senior Physician - South San Francisco at Human Longevity a 6.0 out of 10 for work-life balance — classified as good. This places the position in the Above average in Physician roles — ranked against 20,644 active Physician roles listings on WeekdayDoc.

Internal Medicine — Physician Career Context

Of the 50 active Internal Medicine listings this role was benchmarked against, 8% are remote, 46% have no call, 70% require no weekends.

Internal Medicine pay on WeekdayDoc is down 2.2% vs. the prior quarter (through Sep 2026).

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)). 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Top Internist Jobs

50 matches · ranked by pay

Salary Distribution50 jobs · 36 employers

16
<$315k
13
$315k-345k
14
$345k-375k
6
$375k-405k
1
$425k

Annual compensation range

Benefits & Perks47 jobs · 36 employers

401k / retirement match
87%
CME allowance
64%
Sign-on bonus
57%
Relocation assistance
45%
Loan repayment
36%

Share of similar jobs offering each benefit

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$370k-$425k
#2

Primary Care Physician- Arvada

Impact to Health · Arvada, Colorado

$300k-$400k
#3

Physician

$250k-$400k
#4

Optum CA - Primary Care Physician | Banning, CA

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+ 48 more · ranked by pay

Work-life snapshot

median 6.4this job 6.0
Better work-life than 50% of Internal Medicine listings

Listing-based score, 0–10, across 1,229 comparable listings. Shaded area = the share scoring below this one.

Living in South San Francisco

Typical 3-bedroom home value
$1.23M≈ 6.8× annual pay
Typical market rent
$4,027/mo≈ 27% of gross pay
Residents’ average commute
26 min
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

Human Longevity logo

About Human Longevity

Biotechnology
South San Francisco, California
51-200 employees

Benefits & Perks

Competitive compensation and benefits
Stock Options
Full membership advantages of Human Longevity for personal health
Telemedicine modalities (phone, email, video chat)
World renowned specialists and longevity trailblazers
Buck Institute partnership
Knowledge-based growth opportunities