Takeda logo
Takeda
Boston, Massachusetts

Medical Director Hematology, US OBU Medical Affairs

Medical AffairsFull-Time

Listed compensation

$192k-$302k

The week · per this posting · weekdays assumed

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 3m ago · Verified live

Job Description

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

The US Medical Director, CML & Ph+ ALL provides strategic medical and scientific leadership for Chronic Myeloid Leukemia (CML) and Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL) within US Medical Affairs. The role serves as the US medical subject-matter expert and is accountable for developing and driving the integrated US medical strategy in alignment with evolving science, clinical practice, patient needs, and global medical and development priorities.

How You Will Contribute

Develop and execute the U.S. Medical Affairs strategy and medical plan for leukemia, aligned with broader U.S. and global medical objectives.

Serve as a medical and scientific subject matter expert on leukemia, including disease biology, treatment landscape, emerging science, clinical data, and evolving standards of care.

Translate unmet medical needs and external stakeholder insights into medical priorities, evidence-generation plans, and scientific engagement strategies.

Provide medical leadership for pipeline and launch readiness, including scientific platform development, evidence-gap assessment, stakeholder engagement, and medical education.

Partner with Field Medical to shape scientific engagement priorities, identify actionable insights, and ensure insights are translated into Medical Affairs strategy and execution.

Engage appropriately with key external experts, investigators, cooperative groups, academic institutions, professional societies, and patient-focused organizations to advance scientific exchange and understand evolving needs within leukemia.

Support the development and execution of evidence-generation activities, including company-sponsored Medical Affairs studies, investigator-initiated research, collaborative studies, and real-world evidence initiatives, as appropriate.

Provide medical input into clinical development strategy and study execution, including assessment of unmet need, study concepts, patient populations, endpoints, and the evolving competitive landscape.

Lead or contribute to scientific communication and publication planning, including congress activities, manuscripts, abstracts, medical education, and other scientific materials.

Monitor and evaluate new clinical data, treatment guidelines, competitive developments, and changes in the leukemia treatment landscape and assess their implications for U.S. Medical Affairs strategy.

Collaborate with HEOR/RWE and Market Access partners to identify evidence needs relevant to patient care, treatment decision-making, and healthcare stakeholders.

Provide medical expertise to cross-functional teams while ensuring activities are conducted in accordance with applicable medical, legal, regulatory, compliance, and company standards.

Represent U.S. Medical Affairs on cross-functional and global teams, providing the U.S. medical perspective and ensuring alignment on key strategic priorities.

Develop strong internal and external scientific partnerships to advance the medical strategy and ultimately improve outcomes for patients with leukemia.

Skills and Qualifications

Advanced scientific or medical degree such as MD, DO, PhD, PharmD, or equivalent advanced degree in a relevant discipline.

Strong knowledge of hematologic malignancies, with experience in leukemia or related hematologic cancers strongly preferred.

Understanding of the evolving leukemia treatment landscape, clinical research, therapeutic modalities, and principles of evidence-based medicine.

Experience in Medical Affairs, Clinical Development, or a related scientific/clinical function within the pharmaceutical, biotechnology, academic, or healthcare environment.

Ability to critically evaluate and communicate complex clinical and scientific data to diverse internal and external audiences.

Experience developing or contributing to medical strategy, evidence generation, scientific communications, publications, and external scientific engagement.

Strong understanding of clinical trial design, data interpretation, and application of clinical evidence to Medical Affairs strategy.

Demonstrated ability to work effectively in a cross-functional and matrixed environment, including collaboration with global and U.S. partners.

Strong strategic thinking and ability to translate scientific insights into clear priorities and actionable medical initiatives.

Excellent written and verbal communication, presentation, collaboration, and stakeholder-management skills.

Ability to operate with scientific credibility, sound judgment, and a high degree of accountability and independence.

Understanding of applicable pharmaceutical industry compliance standards and the appropriate role of Medical Affairs.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location

  • Boston, MA
  • U.S. Base Salary Range:
  • $192,400.00 - $302,390.00

The estimated salary range reflects an anticipated range for this position.

The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.

The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

For information about our benefits, please click here.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

  • Locations
  • Boston, MA
  • Worker Type
  • Employee
  • Worker Sub-Type
  • Regular
  • Time Type
  • Full time
  • Job Exempt
  • Yes

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Key Responsibilities

Lead the U.S. Medical Affairs strategy for CML and Ph+ ALL, serving as the medical and scientific subject-matter expert and guiding evidence generation, scientific engagement, and launch readiness. Collaborate with field, clinical development, HEOR/RWE, market access, and global teams to translate scientific insights and patient needs into medical priorities and initiatives.

Requirements

Requires an advanced medical or scientific degree and strong knowledge of hematologic malignancies, with leukemia experience strongly preferred. Candidates should bring relevant Medical Affairs, clinical development, or related experience, along with expertise in clinical research, evidence generation, scientific communication, and cross-functional collaboration.

Qualifications

Experience
10+ years of experience

Key Skills

Clinical Data Interpretation

Medical Affairs — Physician Career Context

The cost-of-living index for Massachusetts is 105.8 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$247k midpoint carries the purchasing power of roughly $234k in an average-cost state. 63.2% of Massachusetts clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Medical Affairs pay on WeekdayDoc is down 2.5% vs. the prior quarter (through Sep 2026).

What does the Medical Affairs market look like in Massachusetts?
MeasureThis jobMarket
Listed pay$192k–$302kMedical Affairs median $300k (middle half $260k–$330k)122 comparable listings, Oct 2026
Cost-of-living adjusted pay~$234k in purchasing powerMassachusetts index 105.8 (US = 100)BEA Regional Price Parities (2024)
Medical Affairs listings in Massachusetts86 active284 nationallylive on WeekdayDoc, Oct 2026
Medical Affairs pay trend−2.5% vs prior quarter—through Sep 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024); as of Oct 2026. Same values as the Weekday Verdict and Market Insights on this page.

Top Medical Affairs Jobs

1 matches · ranked by pay
#1

Sr. Medical Director (Neurologist)

Allucent · Remote - Nationwide

Work-life snapshot

median 3.0this job 1.5
Below most Medical Affairs listings for work-life

Listing-based score, 0–10, across 282 comparable listings. Shaded area = the share scoring below this one.

Living in Boston

Typical 3-bedroom home value
$800k≈ 4.2× annual pay
Typical market rent
$3,271/mo≈ 20% of gross pay
Residents’ average commute
30 min
Metro price indexU.S. average = 100
108.3
State income tax
Up to 5%
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Boston-Cambridge-Newton, MA-NH metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.