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Mayo Clinic
Rochester, Minnesota

Nurse Practitioner or Physician Assistant - Medical Oncology Breast

Physician AssistantFull-Time

Listed compensation

$120k-$167k

The week · per this posting · weekdays assumed

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 48m ago · Verified live

Job Description

Medical Oncology is seeking a Nurse Practitioner (NP) or Physician Assistant (PA) to join the Breast Oncology Care Team in a highly collaborative, academically rich outpatient practice. This is an exciting opportunity to practice at the top of scope while caring for patients with breast cancer across the full continuum of disease and treatment.

The NP or PA will be an integral member of the adult Medical Oncology outpatient practice, partnering closely with physicians, nurses, pharmacists, allied health colleagues, and multidisciplinary specialists to deliver innovative, patient-centered breast cancer care.

NPs and PAs are essential providers in cancer care at Mayo Clinic and function as trusted clinical partners within the oncology care model.

In this role, the NP or PA sees patients at initial consultation in collaboration with an oncologist; independently follows established patients; orders and manages systemic, curative, palliative, and supportive therapies; and guides patients through complex treatment plans.

The role includes management of treatment-related toxicities, symptom burden, survivorship needs, disease assessment, clinical trial care, and end-of-life support.

The practice offers exposure to rapidly evolving treatment advances, including novel systemic therapies, targeted therapies, immunotherapy-based approaches, clinical trials, and precision oncology strategies used in contemporary breast cancer care.

Because of the complexity and breadth of the patient population, the ideal NP or PA candidate will bring strong clinical judgment, excellent assessment and communication skills, intellectual curiosity, and a commitment to caring for patients with challenging and complex oncology needs. Success in this practice requires the ability to balance cancer-directed therapy with symptom management, psychosocial support, shared decision-making, and compassionate longitudinal care.

The NP or PA will work within the focused Breast Oncology Care Team, which includes five collaborative teams composed of physicians, NPs, PAs, RNs, pharmacists, and allied health professionals.

The Breast group works closely with colleagues in Internal Medicine, Surgery, Radiation Oncology, Palliative Care, genetics, pathology, radiology, and other multidisciplinary teams.

The NP or PA will have a central role in advancing continuity of care, supporting timely treatment decisions, serving as a key clinical resource for nursing and allied health colleagues, and coordinating care across disciplines to meet the needs of patients receiving complex and often cutting-edge oncology therapies.

Once established clinically in breast oncology, there is an opportunity to cross train into integrative oncology for interested candidates; this will need to be balanced with practice needs.

In addition, the Department of Oncology and breast tumor group are highly supportive of mentoring NPs and PAs in academic, research, quality improvement, and educational pursuits. We are committed to helping Advanced Practice Providers excel as oncology clinicians, collaborative team members, educators, and contributors to innovation in breast cancer care.

Qualifications

Nurse Practitioner: Masters-prepared or DNP graduate of an accredited school of nursing and Nurse Practitioner program. Current Minnesota RN and APRN license

and certification as a:

  • Family Nurse Practitioner Certification (FNP)
  • Adult Nurse Practitioner Certification (ANP)
  • Acute Care Nurse Practitioner Certification (ACNP)
  • Adult-Gerontology Primary Care Nurse Practitioner Certification (AGNP or

AGPCNP)

Adult-Gerontology Acute Care Nurse Practitioner Certification (AGACNP or ACNPC-AG) Gerontological Nurse Practitioner Certification (GNP) Women’s Health Nurse Practitioner (WHNP)

Physician Assistant: Graduate of accredited Physician Assistant program with current PA certification by NCCPA and registration as a PA by the Minnesota State Board of Medical Practice.

Registration with the U.S. Drug Enforcement Agency (DEA) is required.

BLS is required.

External and Internal candidates for this position are asked to attach a cover letter and 2-3 letters of reference to their online application to be considered for this position.

New graduates please upload 3 letters of reference from preceptors that can attest to your clinical abilities.

Mayo Clinic employees applying for this position are asked to attach 2 most recent performance evaluations to online application to be considered for this position.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Just as our reputation has spread beyond our Minnesota roots, so have our locations.

Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations.

Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Key Responsibilities

The Nurse Practitioner or Physician Assistant will provide comprehensive breast cancer care, including initial consultations, management of systemic therapies, and symptom burden oversight. They will work within a multidisciplinary team to coordinate complex treatment plans and provide longitudinal support to patients.

Qualifications

Education
Doctoral or professional degree (postgraduate degree)
Experience
2+ years of experience

Certifications

DEA License

Key Skills

Patient AssessmentSystemic Therapy ManagementSurvivorship CareMultidisciplinary CollaborationTreatment Planning

Oncology — Physician Assistant Career Context

Mayo Clinic ranks #5 of 18 employers hiring Physician Assistant on WeekdayDoc by average advertised pay.

Of the 50 active Oncology listings this role was benchmarked against, 10% are remote, 72% have no call, 70% require no weekends.

The cost-of-living index for Minnesota is 98.6 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$144k midpoint carries the purchasing power of roughly $146k in an average-cost state. 63.4% of Minnesota clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Top Physician Assistant Jobs

38 matches · ranked by pay

Salary Distribution38 jobs · 30 employers

14
<$145k
5
$145k-165k
10
$165k-185k
6
$185k-205k
3
$205k+

Annual compensation range

Benefits & Perks33 jobs · 30 employers

401k / retirement match
94% this job
CME allowance
67% this job
Sign-on bonus
48%
Relocation assistance
21%
Loan repayment
6%

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Work-life snapshot

median 4.0this job 1.5
Below most Oncology (PA) listings for work-life

Listing-based score, 0–10, across 82 comparable listings. Shaded area = the share scoring below this one.

Living in Rochester

Typical 3-bedroom home value
$307k≈ 2.6× annual pay
Typical market rent
$1,650/mo≈ 17% of gross pay
Residents’ average commute
17 min
Metro price indexU.S. average = 100
90.8
State income tax
Up to 9.8%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Rochester, MN metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

Mayo Clinic logo

About Mayo Clinic

Hospitals and Health Care
Rochester, Minnesota
10,000+ employees

Benefits & Perks

Medical: Multiple plan options
Dental: Delta Dental or reimbursement account
Vision: Affordable plan with national network
Pre-Tax Savings: HSA and FSAs
Retirement: Competitive retirement package
Continuing education and advancement opportunities