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Ophelia
Remote - Nationwide

Telehealth Nurse Practitioner or Physician Assistant (Remote) - Pennsylvania License

Nurse Practitioner 9.3 Work-LifeNo nightsFull-Time

Listed compensation

$110K - $125K

The week · per this posting · Monday – Friday

Weekend work is also flagged as required; confirm which days and how often.

Ask the employer about call expectations and time off.

Posted 6mo ago

Job Description

Are you looking for a role in a company that's solving one of the greatest challenges of our lifetime? Ophelia helps people end their opioid use and restore their quality of life with respect for their time and dignity. Our mission is to make evidence-based treatments for opioid use disorder (OUD) accessible to everyone... and we're looking to bring more people onto our team to help us achieve it.

Ophelia is a venture-backed, healthcare startup that helps individuals with OUD by providing FDA-approved medication and clinical care through a telehealth platform. Our approach is discreet, convenient, and affordable.

We've been successfully operating in 14 states for almost six years and we're excited to continue our growth. We are a team of physicians, scientists, entrepreneurs, researchers and White House advisors, backed by leading technology and healthcare investors working to re-imagine and re-build OUD treatment in America.

About the Role

Clinicians are a critical part of our care team at Ophelia. As an Advanced Practice Practitioner, you will provide clinical care to patients receiving medication for opioid use disorder and a narrow suite of mental health conditions (depression, anxiety, insomnia, etc…).

You’ll work closely alongside other clinicians, triage nurses, and administrative care coordinators to deliver compassionate, evidence-based treatment to patients with OUD.

Our Clinicians offer compassionate, non-stigmatizing support for patients, act as a liaison and advocate for them, and ensure patients receive appropriate care as their needs evolve.

Depending on role type, clinicians conduct Intake visits and/or follow-up visits, and work within a team-based approach model of care to deliver high quality care to our patients.

We have multiple different clinical role types depending on your experience with MOUD, and through our team-based model of care we provide a strong support system to ensure that you and our patients feel comfortable and supported.

Our patient care hours are Monday - Friday 9-7pm and Saturday and Sunday 9-5pm, with our weekend coverage provided only by our most experienced providers! We will work with you to determine your ideal schedule within these hours.

The Ideal Candidate Is an APP Who

  • Has a passion for serving vulnerable populations, and;
  • Either has previous experience caring for individuals with OUD, or willing to learn the clinical skills needed to provide MOUD through a telehealth platform
  • Is looking for full time work in a fast-paced, innovative start-up that values patient-centered care
  • No experience with MOUD is required for this role: we will teach you what you need to know!

In This Role You Will Be Responsible For

Treatment Plans: determine individualized treatment plans for patients; facilitate changes to treatment plans when patients are not improving as expected, either independently or consulting with a more experienced provider.

Behavioral Interventions: use motivational interviewing, behavioral activation and other behavioral interventions as needed to motivate patients to remain in care and adherent to their treatment plan. Conduct behavioral health / psych evals for the suite of psych services we treat (depression, anxiety, insomnia, etc.)

Monitor/Medication Management: systematically track treatment response and monitor patients for changes in clinical symptoms and side effects, treatment adherence, the effectiveness of treatment or complications, and prescribe or queue the appropriate medications

  • Education: provide patient education on OUD and MOUD
  • Charting: Document all patient encounters in Ophelia’s EHR in a timely and high quality manner
  • Training and License Requirements

Board Certified NP or PA

  • Active DEA license (schedule 3N, 4, 5) or willingness to obtain a DEA upon receiving a job offer with Ophelia
  • Fully licensed to practice in Pennsylvania (additional licenses in NJ, NY, VA, or MD a plus!)

Required Skills

  • Ability to provide patient-centered, non-judgmental, non-stigmatizing compassionate care
  • Passionate about working with vulnerable or marginalized populations
  • Comfortable working with a diverse population of people

Proficient and comfortable working in a remote telehealth environment with technological skillset to work across multiple tech platforms

Excited about working in an early-stage healthcare startup that is fast-paced and always evolving processes and technology to meet patient and clinician needs

  • Willing to work in a team-based approach model of patient care
  • Working knowledge of differential diagnosis of common substance use disorders
  • Basic knowledge of psychopharmacology for opioid use disorder
  • Demonstrate ability to collaborate and communicate effectively in a team setting
  • Ability to maintain effective and professional relationships with patients and other members of the care team
  • Working knowledge of evidence-based psychosocial treatments, counseling techniques, or brief behavioral intervention
  • Our Benefits Include

Remote Work Anywhere in the United States

  • Competitive medical, vision, and health insurance (many plans are fully covered for the employee!)
  • Start with 20 days (4 weeks) of PTO, increasing to 5 weeks after 2 years and 6 weeks after 5 years of tenure
  • 10 company holidays
  • Work From Home Stipend
  • 401k Contribution Platform
  • Additional benefits offered through our benefits provider such as life insurance, short and long term disability, financial wellness, virtual primary care, among others!

What Ophelia Offers You

  • Mentorship from national Addiction Medicine experts: meet monthly with our Medical Directors, attend seminars from outside experts in the field, and discuss complicated cases with our clinical leaders
  • Motivated patients: work with patients who are driven to improve their OUD and love being part of Ophelia

Administrative support: outsource all scheduling, pharmacy, and administrative demands to our care coordinators

Referral network for mental health and psychosocial support: rely on our care coordinators to provide referrals and warm handoffs to external services

21st century technology: forget cumbersome EHRs, faxing, and outdated systems. We’ve built our own EHR to ensure you have a smooth and easy charting experience

A say in what matters: help us build better services and products to ensure we always have happy clinicians and happy patients

Please note that total compensation is a base salary & benefits package. Base salary rate is based on experience prescribing MOUD.

Ophelia Compensation Overview

We set compensation based on the level and skills required for the role. We value pay transparency and equity, and are committed to fair pay. In order to prevent pay disparities and reduce time spent in negotiations, we take a “first and best” offer approach: this means we’re not holding any compensation back from our candidates, and you can feel confident that our pay is fair and does not vary based on the strength of someone’s negotiation skills.

Compensation is dynamic at Ophelia: as long as the company performs well and meets our targets, there will be opportunities for increased compensation annually. We’re happy to discuss this approach and our bands if you have questions during the interview process.

Compensation Range

$110,000—$125,000 USD

Interested in learning more about Ophelia and this role? Apply to work with us!

Key Responsibilities

Advanced Practice Practitioners will provide clinical care to patients receiving medication for opioid use disorder and a narrow suite of mental health conditions, determining individualized treatment plans and conducting necessary behavioral health evaluations. Responsibilities also include using motivational interviewing, monitoring treatment response, prescribing medications, and documenting all patient encounters in the EHR.

Requirements

Candidates must be a Board Certified Nurse Practitioner or Physician Assistant, fully licensed to practice in Pennsylvania, and possess an active DEA license or be willing to obtain one upon offer. Experience caring for individuals with Opioid Use Disorder is preferred but not required, as training will be provided for motivated candidates.

Qualifications

Education
Professional certificate or licensure
Experience
2+ years of experience

Certifications

Board Certification

Key Skills

Opioid Use Disorder TreatmentPsychiatric EvaluationEHR DocumentationTeam CollaborationNon-Judgmental CareTelehealth Technology

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Telehealth Nurse Practitioner or Physician Assistant (Remote) - Pennsylvania License at Ophelia a 9.3 out of 10 for work-life balance — classified as exceptional. This places the position in the top 5% in Addiction Medicine (NP) — ranked against 224 active Addiction Medicine (NP) listings on WeekdayDoc. Contributing factors include no night shifts, remote work flexibility.

Addiction Medicine — Nurse Practitioner Career Context

Ophelia holds silver-tier status on WeekdayDoc's Top Employers work-life index, composite score 79/100, 6 active listings.

Of the 43 active Addiction Medicine listings this role was benchmarked against, 16% are remote, 65% have no call, 53% require no weekends — this position is remote.

Addiction Medicine pay on WeekdayDoc is up 5.8% vs. the prior quarter (through Sep 2026).

Top Nurse Practitioner Jobs

16 matches · ranked by pay

Salary Distribution16 jobs · 15 employers

5
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1
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5
$125k-150k
5
$150k-175k

Annual compensation range

Benefits & Perks13 jobs

401k / retirement match
92% this job
Sign-on bonus
62%
CME allowance
46%
Relocation assistance
15%
Loan repayment
8%

Share of similar jobs offering each benefit

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Work-life snapshot

median 6.1this job 9.3
Among the best 10% of Addiction Medicine (NP) listings for work-life

Listing-based score, 0–10, across 224 comparable listings. Shaded area = the share scoring below this one.

  • No nights
  • Remote
  • Includes weekends
Ophelia logo

About Ophelia

Mental Health Care
New York, New York
201-500 employees

Benefits & Perks

Remote Work
Health Insurance
Dental/Vision
20 Days PTO
10 Holidays
Work From Home Stipend
401k Platform
Life Insurance