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Vertex
Boston, Massachusetts · Hybrid

Executive Medical Director, Global Medical Lead (Pain)

Medical AffairsFull-Time

Listed compensation

$328k-$492k

Confirm guaranteed pay, incentives and eligibility with the employer.

Employment & setting
Full-Time · hybrid
Call expectations
Not specified
Weekends
Not specified
Posted 3h ago · Verified live

Job description

Join Vertex Inc. as a Executive Medical Director, Global Medical Lead (Pain) in Boston, Massachusetts, United States.

Benefits & Compensation

  • Salary: $328K - $492K
  • Student loan repayment assistance.
  • Annual bonus eligible
  • Annual equity awards
  • Medical, dental, and vision benefits
  • Generous paid time off including week-long company shutdown in Summer and Winter
  • Commuting subsidy
  • Matching charitable donations
  • 401(k)

Work Schedule

  • Full-Time position.
  • Hybrid position - combination of remote and on-site.
  • Flexible scheduling available.

This position offers hybrid flexibility, competitive compensation, student loan benefits. Work with Vertex Inc. in Boston, Massachusetts, United States.

Key Responsibilities

The Executive Medical Director leads global medical strategy, evidence generation, and cross-functional alignment for the Pain disease area. They are responsible for managing the global medical affairs team, engaging with key external experts, and ensuring scientific excellence across all medical activities.

Requirements

Candidates must hold an MD, PhD, PharmD, or equivalent advanced life sciences degree. The role requires at least 15 years of experience, including 7 years of supervisory experience and 6 years of leadership in medical affairs or clinical development.

Qualifications

Education
Doctoral or professional degree (postgraduate degree)
Experience
10+ years of experience

Key Skills

Scientific leadershipStakeholder managementCross-functional leadershipBudget managementPublication planningKey thought leader engagementMedical monitoringRegulatory compliancePharmacovigilanceStrategic planningTeam leadership

Medical Affairs — Physician Career Context

Vertex holds silver-tier status on WeekdayDoc's Top Employers work-life index, composite score 81/100, 12 active listings.

The cost-of-living index for Massachusetts is 105.8 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$410k midpoint carries the purchasing power of roughly $388k in an average-cost state. 63.2% of Massachusetts clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

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Work-life snapshot

3.9/ 10
Listing-based score

A signal to investigate—not a guarantee about the workplace.

  • Hybrid
Vertex logo

About Vertex

Software Development
King of Prussia, PA
1,001-5,000 employees

Benefits & Perks

Annual bonus eligible
Annual equity awards
Medical, dental, and vision benefits
Generous paid time off including week-long company shutdown in Summer and Winter
Educational assistance programs including student loan repayment
Commuting subsidy
Matching charitable donations
401(k)