Senior/Principal Safety Physician (New Modality)

Astra Zeneca

1 day ago

United StatesFull TimeGeneral Medicine

✓ No Call✓ No Weekends

Apply

Job Description

About the Role

Join AstraZeneca as a Senior/Principal Safety Physician (New Modality) in United States.

Key Responsibilities

Reviews and endorses the Patient Risk Management Plan (PRMP)/Core Patient Risk Log (CPRL).

Provides expertise to the medical content of the safety specification, pharmacovigilance plan and risk minimisation activities in the PRMP, CPRL and globally reviewed LRMPs.

Represents PS on cross

functional Clinical Teams and/or Project Teams for developmental and/or marketed products.

Requirements

Provides input on cross

functional ad

hoc teams set up to address urgent and important safety issues.

May present safety information at clinical investigator and commercial meetings.

Work Schedule

Full-time position.

No explicit call, weekend, or night shift information provided.

Apply to join AstraZeneca as a Senior/Principal Safety Physician (New Modality).

Key Skills

PharmacovigilanceClinical safety strategyPatient risk managementSignal detectionMedical reviewRegulatory complianceDrug developmentClinical study processRisk minimizationSafety surveillanceData evaluationICH guidelinesGCPMedical writingCross-functional collaboration

HealthcareScience & ResearchSecurity & Safetyvia Workday

Position Insights

Work-Life Balance Overview

This Senior/Principal Safety Physician (New Modality) position at Astra Zeneca includes the following lifestyle factors: no on-call duties, no weekend requirements. Candidates should review the full job details to assess overall work-life fit.

General Medicine — Physician Career Context

This General Medicine position at Astra Zeneca is open to physician candidates.

Physicians (MD/DO) are in high demand across healthcare settings, with growing interest in positions that offer sustainable schedules and reduced administrative burden.

Location & Logistics

This position is based in United States.

Why This Position Stands Out

No on-call requirements — clinicians are completely off-duty after hours
No weekend shifts — preserving personal and family time

Skills, Responsibilities & Benefits

Key skills and qualifications: Pharmacovigilance, Clinical safety strategy, Patient risk management, Signal detection, Medical review, Regulatory compliance, Drug development, Clinical study process. Candidates with experience in these areas may be especially well-suited for this General Medicine role.

Core responsibilities: The Senior/Principal Safety Physician is responsible for developing and implementing clinical safety strategies throughout the product development lifecycle. They provide medical expertise for safety surveillance, signal detection, and regulatory documentation while collaborating with cross-function...

About WeekdayDoc

WeekdayDoc is the only healthcare job board that scores every position for burnout risk and work-life balance. Every listing includes a proprietary burnout score, transparent salary data when available, and lifestyle filters for no-call, no-weekends, and remote positions. Browse more General Medicine physician jobs on WeekdayDoc to compare work-life balance scores and compensation across employers.